General Cell Lines and Cell Cultures
As One International Inc Red Fluorescent SH-SY5Y Cell Line, 3 x 10^6 cells/vial
Red Fluorescent SH-SY5Y Cell Line, 3 x 10^6 cells/vial
Cell Biologics Rat Primary Aortic Vascular Smooth Muscle Cells
Rat Primary Aortic Vascular Smooth Muscle Cells
Amsbio LLC Human PANC-1 / Luciferase & GFP (Puro) Cell Line
Human PANC-1 / Luciferase & GFP (Puro) Cell Line
Eurofins Discoverx Ready-to-Assay OXGR1 α-Ketoglutarate Receptor Frozen Cells, 2 Vials of Cells. (HTS191RTA)
The Ready-to-Assay OXGR1 α-Ketoglutarate Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. α-ketoglutarate) based activation of OXGR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses OXGR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of OXGR1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx PathHunter U2OS NF-KB Reporter Cell Line, 2 vials. (93-1157C3)
The PathHunter Signaling Pathway Reporter Assays are stable clonal cell lines that monitor the activation of specific signaling pathways, utilizing the established PathHunter Enzyme Fragment Complementation (EFC) technology. PathHunter U2OS NF-kB Reporter Cell Line is engineered to express a synthetic DNA reporter construct, comprising a NFkB-specific transcription factor response element that drives expression of eProLabel-tagged reporter protein, and takes advantage of endogenous receptors. The activated signaling pathway induces expression of the eProLabel-tagged reporter protein, which is measured by addition of the detection reagent containing EA, resulting in complementation of the two enzyme fragments, and production of an active enzyme that hydrolyzes the substrate to generate a chemiluminescent signal. For detailed product information, User Manual and datasheet, visit www.discoverx.com/pathways.
Eurofins Discoverx ChemiScreen C3aR Anaphylotoxin Receptor Stable Cell Line, 2 vials. (HTS016C)
The ChemiScreen C3aR Anaphylotoxin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. C3a) based activation of C3AR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses C3AR1 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of C3AR1, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx PathHunter C5AR1 Activated GPCR Internalization U2OS Cell Line, 2 vials. (93-0777C3)
The PathHunter C5AR1 Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line uses EFC technology to measure ligand-induced internalization of C5AR1 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged C5AR1. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting C5AR1-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx cAMP Hunter CHO-K1 TSHR (Long Isoform) Gs Cell Line, 2 vials. (95-0153C2)
The cAMP Hunter TSHRL Gs cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. TSH) based activation of TSHRL GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type TSHRL, a naturally Gs coupled GPCR. Upon activation of TSHRL, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC PSN-1; Pancreas Adenocarcinoma; Human (Homo sapiens)
PSN-1 is an epithelial-like cell that was isolated from the pancreas of a 40-year-old, White female with adenocarcinoma. The cell line can be used in testing and calibration in ISO 17025-accredited laboratories, to challenge assay performance, validate or compare test methods, and establish sensitivity, linearity, and specificity during assay validation or implementation.
Miltenyi Biotec, Inc. aIntegrin b7-PE-Vio615,h, m, REA441, 30t
Identification and enumeration of integrin β7+ cells by flow cytometry.
This product is subject to the following: Miltenyi Biotec, Inc. Terms and Conditions of Sale For Products and Services
ATCC Quantitative Genomic DNA from; Campylobacter jejuni; subsp. jejuni; Strain: AS-83-79
Quantitative genomic DNA from Campylobacter jejuni subsp. jejuni can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
Cell Biologics Cas9-Expressing Human Primary Spleen Epithelial Cells
Cas9-Expressing Human Primary Spleen Epithelial Cells
ATCC U-CHCF365; Chordoma; Human (Homo sapiens)
U-CHCF365 (ATCC CRL-3518) is a cell line established from clival tumor material of the chordoma xenograft model CF365.
ATCC Septoria tritici
Major wheat pathogen that causes Septoria tritici blotch. This strain was isolated in 1970 from wheat (Triticum aestivum) in Minnesota, United States. This product is provided as an ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.